A METHODOLOGY TO EVALUATE THE RELIABILITY IMPACT OF THE REPLACEMENT OF WELDED COMPONENTS BY ADDITIVE MANUFACTURING SPARE PARTS

A Methodology to Evaluate the Reliability Impact of the Replacement of Welded Components by Additive Manufacturing Spare Parts

This article shows a method for inspection scheduling of structures made by additive manufacturing, derived from reliability function evaluations and overhaul inspection findings.The routine was an adaption of an existing method developed by the authors for welded components; in this latter case, the routine used a stochastic defect-propagation ana

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Exploration of the Molecular Mechanism of Polygonati Rhizoma in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking

ObjectiveTo explore the effective components and mechanism of Polygonati Rhizoma (PR) in the treatment of osteoporosis (OP) based on network pharmacology and molecular docking methods.MethodsThe effective components and predicted targets of PR were obtained through the Traditional Chinese Medicine Systems Pharmacology and Analysis Platform (TCMSP)

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Retinoid homeostasis in major depressive disorder

Abstract The small, hormone-like molecule retinoic acid (RA) is a vital regulator in several neurobiological processes that are affected in depression.Next to its involvement in dopaminergic signal transduction, neuroinflammation, and neuroendocrine regulation, recent studies highlight the role of RA in homeostatic synaptic plasticity and its link

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